COVID-19: Global Supply Chain Update May 7th, 2020 As part of our continued work during the COVID-19 crisis, we are keeping you up to date on the supply chain. Below you will find some of the key updates happening around the world. Yourway remains fully operational despite challenges presented. We are continuing to support ongoing clinical trials to develop life-saving medicines via our DTP service offering, and have been able to keep up our everyday operations while ensuring the safety of our staff, throughout the pandemic. Global News Brief Mesoblast, a Melbourne-based biotech company, began enrolling up to 300 patients for a randomized, controlled study of its stem cell therapy remestemcel-L for the treatment of COVID-19. Over 20 hospitals will participate in the study, which is anticipated to last 3-4 months. Beaumont Health has launched a new clinical study aimed at treating COVID-19 patients with a combination of naltrexone and ketamine. Alnylam and Vir Biotechnology are working on an anti-SARS-CoV-2 inhaled RNAi candidate, which is expected to begin in-human testing by the end of the year. China is in the race to develop a vaccine for COVID-19, and four Chinese companies have already started testing vaccine candidates on humans.      Regional Breakdown North America USA Several states have reopened fully, including Georgia. Passenger flights continue to operate on a reduced timeline, putting more strain on commercial flights. The U.S. borders with Canada and Mexico will remain closed until mid-May. Though formal restrictions vary by state, road travel remains open, with trucking demand increasing. Major U.S. airports remain operational, with flights limited from individual carriers in both domestic and international lanes, and ongoing limitations from smaller ports. Non-essential travel is limited both domestically and internationally. Ocean carriers are fully operational and following standard crisis protocols, but cargo transport between China and North America is significantly reduced.      Canada A total of five provinces have reopened, though others remain in a state of emergency. Air Canada flights have been suspended to the U.S. until May 27. International flights may only land at international airports in Montreal, Toronto, Calgary, and Vancouver as an enhanced screening measure. Air Canada’s international flights have been suspended through June. Air Transat and Sunwing Airlines flights remain canceled until May 30. Trade across the border is unaffected, and supply chains remain intact.      Mexico Non-essential travel continues to be restricted. Air-freight capacity is reduced due to ongoing flight cancellations. The U.S.-Mexico border will remain closed for an additional 30 days. Nationwide restrictions have been extended through May 30. Commercial flights have been reduced, but cargo is unaffected. All non-essential activities are banned until April 30th, and all citizens have been urged to stay at home. Air, ocean, and road traffic are all still operational--Yourway’s operations remain unaffected.      Europe United Kingdom The London City Airport will not reopen until May 30. British Prime Minister Boris Johnson cautioned against easing restrictions too soon and will revisit the lockdown terms on May 7. British Airways has suspended all flights to and from London's Gatwick Airport. Only 2 out of 4 terminals are operational at Heathrow Airport. Although most passenger transit is significantly reduced, goods are still moving freely into and around the UK.      Germany Weekend traffic bans have been lifted on trucks, with the German Federal government requesting a separate freight lane for the transportation of medical goods. Bavaria has lifted its driving ban on Sundays and public holidays until May 30. The Land of Hesse has lifted its driving ban on Sundays and days holidays to all goods transport vehicles until June 30. Eurail service has been reduced to the Netherlands. Germany is slowly reversing lockdown restrictions. Passengers arriving from a non-Schengen member state are not allowed to enter Germany. Border crossing is allowed between neighboring countries, excluding Belgium and the Netherlands. Air travel capacity has been reduced, affecting regional hubs and Lufthansa specifically though cargo continues.      France The nation will begin to gradually lift certain lockdown conditions on May 11. Flights are reduced between France and the United States and some of the most impacted countries, including China and Italy. Overseas flights are limited to maintaining territorial continuity Schengen borders remain closed. Orly Airport has been closed since April 1. Travelers being evacuated from other countries by the French government must undergo quarantine.      Sweden Entry restrictions have been extended to May 16. All non-essential businesses are open.      Italy Lockdown restrictions eased beginning May 4, with many nonessential workers returning to their jobs, largely in manufacturing. Travel restrictions have been partially lifted. Transport by road and rail remains operational.      Spain Spain has initiated a four-phase plan to end lockdown. Travel remains restricted and is reserved for essential travel. The national lockdown has been extended until May 9. Land borders are closed to entry but not for cargo, allowing clinical trial materials and DTP services to continue. Airports, ports, warehouses, and carriers remain open and operational.      Poland Lockdown restrictions will be slowly lifted in accordance with a 4-stage plan. No international inbound flights or trains have been allowed entry into the country since March 15. The borders remain open to the movement of goods, and trucks bearing international road freight are no longer required to respect a quarantine period of two weeks. Borders are to remain closed until May 3, with a state of emergency enforced until April 19.      Russia    Foreign nationals are not allowed to re-enter the country. Non-essential businesses have been mandatorily closed. An overnight curfew was implemented in Chechnya, with road, rail, and air transport links suspended in the region. All commercial, international, and charter flights are suspended.

Asia Pacific

China

	Travel restrictions lifted on April 30.
	Schools reopened in China’s major cities.
	The land border between Russia and China remains closed.
	Passenger and international flights are limited, with cargo unaffected.
	There have been minimal changes to import and export regulations.

Hong Kong

	Travel restrictions will begin to lessen after May 7.
	The Hong Kong government predicts the country will be back on track by July.
	Nonresidents from any location outside mainland China, Macau, and Taiwan were banned from entering Hong Kong starting March 25th.
	Nonresidents from mainland China, Macau, and Taiwan who were overseas in the previous 14 days are also barred from entry.
	All flights have been suspended from the Hong Kong International Airport.

South Korea

	Restrictions will be eased starting May 6.
	South Korea has lifted bans in even high-risk establishments, including places of worship, bars, and sporting facilities.
	Seoul’s defense ministry is considering easing restrictions on travel and guest visits.

Singapore

	Flight cancellations have been extended through the end of June.
	Terminal 2 of the Changi Airport will be inactive for 18 months.
	Country-wide restrictions are in effect until June 1.

India

	Air cargo and port operations are active.
	Restrictions have been eased overall.
	International and domestic flights resumed beginning May 3.

Australia

	Western Australia, New South Wales, and Queensland have eased lockdown restrictions.
	Virgin Airlines limited domestic flight service will resume until June 7, cargo is not affected.

New Zealand

	Lockdown restrictions will be re-evaluated on May 11.
	Freight flights are operating under limitations, with service exclusive to Auckland, Wellington, Christchurch, Nelson, and Dunedin.

Middle East

Israel

	The Israeli government has approved steps to ease restrictions.
	Transit facilities at Tel Aviv (TLV) are temporarily suspended.
	The Israeli border remains closed to all, except nationals, residents, and those with a specific entry approval from the Immigration Authority.

Saudi Arabia

	The Saudi government has permitted the entry to and exit from the Qatif province in efforts to ease restrictions.
	Dammam is under an indefinite 24-lockdown that began on May 2, with entry to and from the area banned.
	Traveling is restricted between regions.
	International flights are suspended but freight and commercial flights remain available.

Turkey

	Turkish Airlines has suspended all flights until May 28.
	Lockdown restrictions were eased starting May 3.
	The government has expanded flight restrictions to a total of 68 countries, cargo is not affected.

South America

Chile

	Limited domestic flights are available through LATAM Airlines.
	International flights remain suspended until the end of May.
	A nationwide curfew is in place until June 17.
	Borders remain closed to non-resident foreigners.
	Cargo transport is not restricted, including ports, airports, and customs processing.

Brazil

	Quarantine restrictions are in effect in São Paulo until May 10.
	Customs agents are limited to two working days a week.
	The U.S. government is considering limiting travel from Brazil.

Argentina

	Lockdown measures are in effect until May 10.
	Argentina bans all flights in and out of the country until September 1, establishing one of the world’s most intensive travel restrictions.
	Medical supplies and other essential cargo are not affected.

Africa

South Africa

	Lockdown restrictions were eased beginning May 1.
	Domestic flights are currently suspended.

Nigeria

	Aviation minister Hadi Sirika announced that Nigeria will extend the closure of its airspace and airports by two weeks, effective April 20.
	Nigeria has extended its original three-week lockdown for an additional two weeks, effective April 13.
	Nigeria has placed a complete travel ban on 13 countries.

Thank you for reading the Yourway newsletter. As we navigate the current global situation, our priority is to keep our customers abreast of ongoing developments, including border closures and openings.

Our 21 global depots are operating at full capacity and we continue to deliver clinical trial materials around the world and directly to patients without issue.

If your company is experiencing disruptions or challenges in your supply chain, contact Yourway for solutions to your specific needs.

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